PART VI Non-narcotic analgesics
01. Non-narcotic analgesics are mainly effective against pain associated with:
a) Inflammation or tissue damage
b) Trauma
c) Myocardial infarction
d) Surgery
02. Non-narcotic agents cause:
a) Respiratory depression
b) Antipyretic effect
c) Euphoria
d) Physical dependence
03. Non-narcotic analgesics are all of the following drugs EXCEPT:
a) Paracetamol
b) Acetylsalicylic acid
c) Butorphanol
d) Ketorolac
04. Select the non-narcotic drug, which is a paraaminophenol derivative:
a) Analgin
b) Aspirin
c) Baclophen
d) Paracetamol
05. Which of the following non-narcotic agents is salicylic acid derivative?
a) Phenylbutazone
b) Ketamine
c) Aspirin
d) Tramadol
06. Tick pirazolone derivative:
a) Methylsalicylate
b) Analgin
c) Paracetamol
d) Ketoralac
07. Which one of the following non-narcotic agents inhibits mainly cyclooxygenase (COX) in CNS?
a) Paracetamol
b) Ketorolac
c) Acetylsalicylic acid
d) Ibuprofen
08. Most of non-narcotic analgetics have:
a) Anti-inflammatory effect
b) Analgesic effect
c) Antipyretic effect
d) All of the above
09. Indicate the non-narcotic analgesic, which lacks an anti-inflammatory effect:
a) Naloxone
b) Paracetamol
c) Metamizole
d) Aspirin
10. Correct statements concerning aspirin include all of the following EXCEPT:
a) It inhibits mainly peripheral COX
b) It does not have an anti-inflammatory effect
c) It inhibits platelet aggregation
d) It stimulates respiration by a direct action on the respiratory center
11. For which of the following conditions could aspirin be used prophylactically?
a) Noncardiogenic pulmonary edema
b) Peptic ulcers
c) Thromboembolism
d) Metabolic acidosis
12. All of the following are undesirable effects of aspirin EXCEPT:
a) Gastritis with focal erosions
b) Tolerance and physical addiction
c) Bleeding due to a decrease of platelet aggregation
d) Reversible renal insufficiency
13. Characteristic findinds of salicylism include:
a) Headache, mental confusion and drowsiness
b) Tinnitus and difficulty in hearing
c) Hyperthermia, sweating, thirst, hyperventilation, vomiting and diarrhea
d) All of the above
14. Analgin usefulness is limited by:
a) Agranulocytosis
b) Erosions and gastric bleeding
c) Methemoglobinemia
d) Hearing impairment
15. Methemoglobinemia is possible adverse effect of:
a) Aspirin
b) Paracetamol
c) Analgin
d) Ketorolac
16. Correct the statements concerning ketorolac include all of the following EXCEPT:
a) It inhibits COX
b) It is as effective as morphine for a short-term relief from moderate to severe pain
c) It has a high potential for physical dependence and abuse
d) It does not produce respiratory depression
17. Indicate the nonopioid agent of central effect with analgesic activity:
a) Reserpine
b) Propranolol
c) Clopheline
d) Prazosin
18. Select the antiseizure drug with an analgesic component of effect:
a) Carbamazepine
b) Ethosuximide
c) Phenytoin
d) Clonazepam
19. Which of the following nonopioid agents is an antidepressant with analgesic activity?
a) Fluoxetine
b) Moclobemide
c) Tranylcypramine
d) Amitriptyline
20. Tick mixed (opioid/non-opioid) agent:
a) Paracetamol
b) Tramadol
c) Sodium valproate
d) Butorphanol
