51. Cortisol ?
A. Secretion increases following injury
B. Favours protein synthesis
C. Enhances antigen – antibody reactions
D. Tends to lower blood pressure
52. All are seen in Cushing ‘s syndrome except ?
A. Truncal obesity
B. Hypertension
C. Hypoglycemia
D. Poor wound healing
53. Which is false regarding insulin ?
A. Secreted by beta cells
B. Glycopeptide
C. Causes lipogenesis
D. Promotes glycogenesis
54. Human chorionic gonadotrophin hormone ( HCG) ?
A. Acts on the uterus to maintain integrity of endometrium in early pregnancy
B. Production is greatest in the last three months of pregnancy
C. Can be identified in the urine of pregnant women by immunological technique
D. Is a steroid hormone
55. Regarding myxedema the following are true except ?
A. Swollen, oedematous look of the face
B. Impotency, amenorrhea
C. B.M.R increased by 30 -45%
D. Dullness, loss of memory
56. The catecholamines secreted by adrenal medulla ?
A. Increases the blood glucose level by favoring glycogenolysis in blood and muscle cells
B. Decrease the level o free fatty acids and ketone bodies
C. Increase the splanchnic blood flow
D. Are under the control of parasy
57. In thyrotoxicosis , there is ?
A. Decrease in calcium excretion
B. Increase in serum proteins which bind throxine
C. Potentiation of catecholamine action
D. Increase in calcium excretion
58. Progesterone production in the ovary is primarily by ?
A. Stroma
B. Corpora albicans
C. Corpora lutea
D. Mature follicles
59. All the following hormones are secreted by adrenal cortex except ?
A. Estriol
B. Cortisol
C. Corticosterone
D. Aldosterone
60. Contraceptive action of combined pill is mainly due to ?
A. Decrease in tubal motility
B. Prevents the fertilization
C. Prevents the implantation of fertilized egg
D. Inhibits ovulation
61. Epinephrine is most closely related in structure to
?
A. Niacin
B. Tyrosine
C. Methionine
D. Glycerol
62. Steroid hormones are believed to enter target cells via ?
A. Facilitated diffusion
B. Carrier – mediated endocytosis
C. Cholesterol lined pores in the plasma membrane
D. Simple diffusion
63. Which of the following statements about the action of the somatomedin is true ?
A. They inhibit protein synthesis
B. They antagonize the effect of insulin
C. They promote growth of bone and cartilage
D. They mediated the local effects of Somatostatin
64. Hormone released during increased stress is ?
A. Cortisol
B. Thyroxine
C. Growth hormone
D. Somatostatin
65. Features of hypothyroidism does not include ?
A. Obseity
B. Hypertension
C. High TSH levels
D. Increased risk of infections
66. The primary site of action of antidiuretic hormone is on the ?
A. Distal tubules and collecting ducts in the kidney
B. Afferent arterioles of the glomeruli
C. Thirst center in the hypothalamus
D. Osmoreceptors in the hypothalamus
67. The hormone , which stimulates uterus contraction and lets down milk, is ?
A. Progesterone
B. Prolactin
C. Prostaglandin
D. Oxytocin
68. Which hormone does not have corresponding release hormone produced in pituitary ?
A. TSH
B. Prolactin
C. ACTH
D. FSH
69. Thyroxine causes all the following except ?
A. Decreased cell metabolism
B. Increased oxygen consumption
C. Increased pulmonary ventilation
D. Increased basal metabolism
70. Which of the following hormones increase the sensitivity of heart to epinephrine ?
A. Parathyroid
B. Insulin
C. Thyroid
D. Glucagon
71. Which of the following is called hunger hormone ?
A. Epinephrine
B. Glucagon
C. Pituitary
D. Thyroxine
72. Posterior pituitary insufficiency leads to ?
A. Diabetes mellitus
B. Diabetes insipidus
C. Dwarfism
D. Cretinism
73. The blood glucose level in diabetes mellitus is decreased by removal of the ?
A. Thyroid
B. Parathyroids
C. Anterior pituitary
D. Posterior pituitary
74. Adrenaline used for controlling of bleeding during surgery may result in ?
A. Syncope
B. Cardiac arrhythmias
C. Drastic fall in blood pressure
D. Precipitation of allergic reaction
75. The primary effect of calcitonin is ?
A. Bone deposition
B. Bone resorption
C. Increases intestinal absorption of calcium
D. Decreases intestinal absorption of calcium
76. The decreased phosphate level seen in hyper parathyroidism is due to
?
A. Decreased intestinal phosphate absorption
B. Increased calcium excretion
C. Decreased renal phosphate absorption
D. Increased loss of phosphate in urine
77. The hormone whose deficiency causes diabetes insipidus is released from which nucleus of pituitary ?
A. Supraoptic
B. Pre optic
C. Suprachiasmatic
D. Paraventricular
78. Aldosterone production is controlled by ?
A. Anterior pituitary gland
B. Posterior pituitary gland
C. Hypothalamus
D. Adrenal gland
79. Hormones, which stimulate spermatogenesis, are ?
A. Insulin and glucagon
B. Thyroxine and parathormone
C. A.D.H. and Oxytocin
D. Testosterone and F.S. H
80. Which of the following results due to excessive parathormone secretion ?
A. Increased excretion of phosphates
B. Increased serum calcium
C. Decrease excretion of calcium
D. Increase excretion of calcium
81. Bone metabolism is controlled by ?
A. Vit – D & Calcium
B. Parathormone
C. Calcitonin
D. All of the above
82. Changes in biological activity occurring daily are referred as rhythm?
A. Circadian
B. Circa triginatan
C. Circa sestin
D. Circannual
83. Iodine is primarily important in the biochemical synthesis of ?
A. ACTH
B. Thyroxine
C. Adrenaline
D. Calcitonin
84. Trousseau’s sign and chovstek’s sings are positive in ?
A. Hyperparathyroidism
B. Hypothyroidism
C. Hypoparathyroidism
D. Hyperthyroidism
85. Vasopressin is synthesized in the ?
A. Anterior pituitary
B. Hypothalamus
C. Juxtaglomerular apparatus
D. Vasomotor center
86. Aldosterone ?
A. Increases reabsorption of sodium
B. Increases exceretion of potassium
C. Increases retention of sodium
D. Both ‘A’ and ‘B’
87. A phaeochromocytoma is a tumour of the ?
A. Adrenal cortex
B. Parathyroids
C. Pituitary
D. None of the above
88. Which of the following is associated with a low concentration of ionized calcium in the serum ?
A. Hypothyroidism
B. Osteogenesis imperfecta
C. Paget’s disease of the bone
D. Tetany
89. Which of the following hormones is released from the posterior pituitary ?
A. ACTH
B. Antidiuretic hormone
C. Growth hormone
D. Luetinizing hormone
90. All of the following are adverse effects of long- term corticosteroids EXCEPT ?
A. Hypoglycemia
B. Psychosis
C. Peptic ulcers
D. Osteoporosis
91. Which amongst the following is the gold standard for demonstrating hcG ?
A. Radio immune assay
B. Latex agglutination
C. Immunofluorescence
D. ELISA
92. Which one of the following is a precursor of both gonadal and adrenocortical hormones ?
A. Progesterone
B. Cortisol
C. Testosterone
D. Corticosterone
93. Inhibit b hormone has effect on ?
A. Sertoli cells
B. FSH
C. Seminiferous tubules
D. Spermatogenesis
94. Glucose tolerance test is usually done to assess ?
A. Acute Pancreatitis
B. Carcinoma of Head of Pancreas
C. Acinar Function of the Pancreas
D. Endocrine Dysfunction of Pancreas
95. Which of the following hormones act via cAMP ?
A. Insulin
B. Parathormone
C. Vasopressin
D. Adrenalin
96. Insulin increases the activity of ?
A. HMG. CoA reductase
B. HMG- CoA lyase
C. HMG- CoA synthase
D. Thiolase
97. Hyperthyroidism can be caused by ?
A. Clonidine
B. Amiodarone
C. Hydralazine
D. Penicillamine
98. Hormones FSH & LH of anterior pituitary gland acts on ?
A. Testis but not ovaries
B. Ovaries but not testis
C. Both Testis and ovaries
D. Adrenal cortex
99. Removal of parathyroid gland produces the following changes EXCEPT ?
A. Decline plasma calcium level
B. Decrease in plasma phosphate level
C. Neuromuscular hyperexcitability
D. hypo calcemic tetany
100. Fertilized ovum usually gets attached to the uterus wall in ?
A. 14 days
B. 28 days
C. 8 weeks
D. 1 week
